{"cik":"0001111312","entityType":"operating","sic":"8731","sicDescription":"Services-Commercial Physical & Biological Research","ownerOrg":null,"insiderTransactionForOwnerExists":0,"insiderTransactionForIssuerExists":1,"name":"CytoCore, Inc.","tickers":[],"exchanges":[],"ein":"330374014","lei":null,"description":"","website":"","investorWebsite":"","category":"","fiscalYearEnd":"1231","stateOfIncorporation":"DE","stateOfIncorporationDescription":"DE","addresses":{"mailing":{"street1":"3520 DUNHILL STREET","street2":null,"city":"SAN DIEGO","stateOrCountry":"CA","zipCode":"92121","stateOrCountryDescription":"CA","isForeignLocation":null,"foreignStateTerritory":null,"country":null,"countryCode":null},"business":{"street1":"3520 DUNHILL STREET","street2":null,"city":"SAN DIEGO","stateOrCountry":"CA","zipCode":"92121","stateOrCountryDescription":"CA","isForeignLocation":null,"foreignStateTerritory":null,"country":null,"countryCode":null}},"phone":"5855974990","flags":"","formerNames":[{"name":"APPLIED MOLECULAR EVOLUTION INC","from":"2000-07-26T00:00:00.000Z","to":"2004-02-13T00:00:00.000Z"}],"filings":{"recent":{"accessionNumber":["0000950137-06-007446","0000950137-04-000876","0001244834-04-000011","0001244834-04-000010","0001244834-04-000009","0001244834-04-000008","0001244834-04-000007","0001244834-04-000006","0000898432-04-000116","0000950124-04-000252","0000898432-04-000054","0000950137-04-000115","0001055947-04-000004","0001055947-04-000003","0001055947-04-000002","0001244834-04-000004","0001244834-04-000003","0001244834-04-000002","0001244834-04-000001","0000936392-04-000002","0000936392-03-001635","0000950137-03-006186","0000936392-03-001631","0000936392-03-001630","0000936392-03-001629","0000936392-03-001628","0000950137-03-006100","0000936392-03-001487","0000936392-03-001486","0001244834-03-000009","0001244834-03-000008","0001244834-03-000007","0000936392-03-001058","0000936392-03-001057","0001244834-03-000006","0001244834-03-000005","0001244834-03-000004","0001244834-03-000003","0001244834-03-000002","0000936392-03-000644","0000936392-03-000643","0000936392-03-000536","0000936392-03-000217","0000936392-03-000170","0001047469-03-004937","0001047469-03-003473","0000892569-03-000004","0000892569-03-000003","0000936392-02-001338","0000936392-02-001333","0000936392-02-001332","0000936392-02-001331","0000912057-02-038107","0000912057-02-037900","0000912057-02-037645","0000892569-02-001971","0000912057-02-035757","0000912057-02-035598","0000912057-02-035361","0000912057-02-034919","0000912057-02-034780","0000912057-02-034610","0000892569-02-001854","0000936392-02-001040","0000912057-02-024460","0000912057-02-024380","0000936392-02-000658","0000936392-02-000524","9999999997-02-030473","0000936392-02-000480","0000936392-02-000186","0001104659-02-000483","0000936392-02-000143","0000936392-02-000142","0001047469-02-000064","0000936392-01-500299","0000936392-01-500195","0001095811-01-503715","0001095811-01-502810","0000902664-01-500200","0001095811-01-502060","0001095811-01-502056","0001095811-01-501703","0001095811-01-501446","0001095811-01-001646","0001095811-01-001359","0001095811-01-001356","0000950005-01-000286","0001047469-01-000178","0001095811-00-004494","0000902664-00-000632","0000902664-00-000631","0001095811-00-003269","0001095811-00-002249","0001095811-00-002131","0001095811-00-002118","0001095811-00-002102","0000936392-00-000387","0000936392-00-000378","0000936392-00-000377","0000936392-00-000368","0001095811-00-001794","0001095811-00-001389"],"filingDate":["2006-06-29","2004-02-13","2004-02-11","2004-02-11","2004-02-11","2004-02-11","2004-02-05","2004-02-05","2004-02-04","2004-01-29","2004-01-20","2004-01-13","2004-01-12","2004-01-08","2004-01-06","2004-01-05","2004-01-05","2004-01-05","2004-01-05","2004-01-02","2003-12-01","2003-12-01","2003-11-21","2003-11-21","2003-11-21","2003-11-21","2003-11-21","2003-11-04","2003-11-04","2003-09-23","2003-09-17","2003-09-17","2003-08-05","2003-08-05","2003-07-09","2003-07-07","2003-07-03","2003-07-03","2003-07-03","2003-05-06","2003-05-06","2003-04-24","2003-03-04","2003-02-14","2003-02-12","2003-01-31","2003-01-02","2003-01-02","2002-11-05","2002-11-05","2002-11-05","2002-11-05","2002-10-09","2002-10-07","2002-10-03","2002-09-23","2002-09-17","2002-09-16","2002-09-12","2002-09-09","2002-09-06","2002-09-05","2002-08-21","2002-08-14","2002-06-17","2002-06-14","2002-05-30","2002-05-07","2002-04-30","2002-04-29","2002-03-05","2002-02-14","2002-02-14","2002-02-14","2002-02-01","2001-11-16","2001-11-06","2001-08-07","2001-06-15","2001-06-08","2001-05-11","2001-05-11","2001-05-01","2001-04-23","2001-03-19","2001-02-14","2001-02-14","2001-02-14","2001-02-07","2000-11-09","2000-10-17","2000-10-17","2000-09-08","2000-08-03","2000-07-27","2000-07-26","2000-07-26","2000-07-26","2000-07-21","2000-07-20","2000-07-05","2000-06-26","2000-05-12"],"reportDate":["2006-05-30","","2004-02-09","2004-02-09","2004-02-09","2004-02-09","2004-02-03","2004-02-03","","","2004-01-08","","2004-01-08","2004-01-06","2004-01-02","2004-01-02","2004-01-02","2004-01-02","2004-01-02","","","","2003-11-21","","","2003-11-21","","2003-11-04","2003-09-30","2003-09-19","2003-09-15","2003-09-15","2003-08-05","2003-06-30","2003-07-07","2003-07-01","2003-07-01","2003-07-01","2003-07-01","2003-03-31","2003-05-06","2003-05-22","2002-12-31","","","","","","2002-09-30","2002-11-05","","2002-06-30","2002-10-07","2002-10-03","2002-10-01","2002-09-20","2002-09-13","2002-09-12","2002-09-03","2002-09-05","","2002-09-03","2002-08-18","2002-06-30","","","","2002-03-31","2001-12-31","2002-05-29","2001-12-31","","","","","","2001-09-30","2001-06-30","","2001-06-08","2001-04-16","","2001-03-31","2001-05-31","2000-12-31","","","","","2000-09-30","","2000-09-30","2000-06-30","","","","","","","","","",""],"acceptanceDateTime":["2006-06-29T20:03:19.000Z","2004-02-12T22:35:04.000Z","2004-02-11T21:48:40.000Z","2004-02-11T21:07:28.000Z","2004-02-11T20:19:02.000Z","2004-02-11T20:18:21.000Z","2004-02-05T23:05:54.000Z","2004-02-05T20:19:16.000Z","2004-02-04T19:15:26.000Z","2004-01-29T19:09:42.000Z","2004-01-20T21:22:28.000Z","2004-01-13T01:15:18.000Z","2004-01-12T22:18:46.000Z","2004-01-08T22:15:12.000Z","2004-01-06T22:54:00.000Z","2004-01-05T23:32:54.000Z","2004-01-05T23:31:49.000Z","2004-01-05T23:30:22.000Z","2004-01-05T23:29:12.000Z","2004-01-02T22:06:58.000Z","2003-12-01T21:48:50.000Z","2003-12-01T21:42:14.000Z","2003-11-21T22:12:25.000Z","2003-11-21T22:11:16.000Z","2003-11-21T22:10:03.000Z","2003-11-21T22:08:52.000Z","2003-11-21T22:02:58.000Z","2003-11-04T22:25:07.000Z","2003-11-04T22:21:03.000Z","2003-09-23T18:53:33.000Z","2003-09-17T15:18:58.000Z","2003-09-17T15:17:31.000Z","2003-08-05T20:54:44.000Z","2003-08-05T20:50:34.000Z","2003-07-09T16:05:23.000Z","2003-07-03T21:42:39.000Z","2003-07-03T20:02:19.000Z","2003-07-03T20:01:31.000Z","2003-07-03T20:00:22.000Z","2003-05-06T20:22:59.000Z","2003-05-06T20:21:49.000Z","2003-04-24T20:09:05.000Z","2003-03-04T22:27:39.000Z","2003-02-14T20:39:55.000Z","2003-02-12T19:30:27.000Z","2003-01-31T17:57:54.000Z","2003-01-02T13:08:01.000Z","2003-01-02T13:07:13.000Z","2002-11-05T21:23:09.000Z","2002-11-05T17:59:42.000Z","2002-11-05T17:51:52.000Z","2002-11-05T17:41:27.000Z","2002-10-09T19:00:13.000Z","2002-10-07T20:07:50.000Z","2002-10-03T20:59:04.000Z","2002-09-23T12:05:18.000Z","2002-09-17T19:22:46.000Z","2002-09-16T16:31:15.000Z","2002-09-12T20:48:36.000Z","2002-09-09T21:15:27.000Z","2002-09-06T20:38:49.000Z","2002-09-05T17:42:35.000Z","2002-08-21T12:04:41.000Z","2002-08-14T19:17:50.000Z","2002-06-17T19:27:43.000Z","2002-06-14T21:27:45.000Z","2002-05-30T21:16:13.000Z","2002-05-07T20:44:15.000Z","2002-05-21T15:54:15.000Z","2002-04-29T20:43:20.000Z","2002-03-05T05:00:00.000Z","2002-02-14T05:00:00.000Z","2002-02-14T05:00:00.000Z","2002-02-14T05:00:00.000Z","2002-02-01T05:00:00.000Z","2001-11-16T05:00:00.000Z","2001-11-06T05:00:00.000Z","2001-08-07T04:00:00.000Z","2001-06-15T04:00:00.000Z","2001-06-08T04:00:00.000Z","2001-05-11T04:00:00.000Z","2001-05-11T04:00:00.000Z","2001-05-01T04:00:00.000Z","2001-04-23T04:00:00.000Z","2001-03-19T05:00:00.000Z","2001-02-14T05:00:00.000Z","2001-02-14T05:00:00.000Z","2001-02-14T05:00:00.000Z","2001-02-07T05:00:00.000Z","2000-11-09T05:00:00.000Z","2000-10-17T04:00:00.000Z","2000-10-17T04:00:00.000Z","2000-09-08T04:00:00.000Z","2000-08-03T04:00:00.000Z","2000-07-27T04:00:00.000Z","2000-07-26T04:00:00.000Z","2000-07-26T04:00:00.000Z","2000-07-26T04:00:00.000Z","2000-07-21T04:00:00.000Z","2000-07-20T04:00:00.000Z","2000-07-05T04:00:00.000Z","2000-06-26T04:00:00.000Z","2000-05-12T04:00:00.000Z"],"act":["34","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","","",""],"form":["8-K","15-12G","4","4","4","4","4","4","SC 13G/A","425","4/A","425","4","4","4","4","4","4","4","425","SC 13D","SC 13D","8-K","8-A12G/A","DEFA14A","8-K","425","8-K","10-Q","4","4","4","8-K","10-Q","4","4","4","4","4","10-Q","8-K","DEF 14A","10-K","SC 13G/A","SC 13G/A","SC 13G/A","S-8","S-8","10-Q","8-K","8-A12G/A","10-Q/A","4","4","4","8-K","4","4","3","4","SC 13G/A","4","8-K","10-Q","SC 13G/A","SC 13G","S-8","10-Q","ARS","DEF 14A","10-K","SC 13G/A","SC 13G/A","SC 13G/A","SC 13G","S-8","10-Q","10-Q","SC 13G/A","4","8-K","8-A12G","10-Q","DEF 14A","10-K","SC 13G","SC 13G","SC 13G","SC 13G","10-Q","SC 13D","5","10-Q","S-8","424B4","S-1MEF","S-1/A","S-1/A","S-1/A","8-A12G","S-1/A","S-1/A","S-1"],"fileNumber":["000-31101","000-31101","","","","","","","005-59733","000-31101","","000-31101","","","","","","","","000-31101","005-59733","005-59733","000-31101","000-31101","000-31101","000-31101","000-31101","000-31101","000-31101","","","","000-31101","000-31101","","","","","","000-31101","000-31101","000-31101","000-31101","005-59733","005-59733","005-59733","333-102317","333-102316","000-31101","000-31101","000-31101","000-31101","000-31101","000-31101","000-31101","000-31101","000-31101","000-31101","000-31101","000-31101","005-59733","000-31101","000-31101","000-31101","005-59733","005-59733","333-89416","000-31101","000-31101","000-31101","000-31101","005-59733","005-59733","005-59733","005-59733","333-73584","000-31101","000-31101","005-59733","000-31101","000-31101","000-31101","000-31101","000-31101","000-31101","005-59733","005-59733","005-59733","005-59733","000-31101","005-59733","000-31101","000-31101","333-42924","333-36830","333-42298","333-36830","333-36830","333-36830","000-31101","333-36830","333-36830","333-36830"],"filmNumber":["06933853","04593080","","","","","","","04566151","04551728","","04521570","","","","","","","","04501649","031030422","031030397","031018883","031018869","031018859","031018849","031018784","03977250","03977165","","","","03824247","03824220","","","","","","03684500","03684487","03662489","03592070","03567524","03553887","03533971","03500006","03500005","02809993","02809476","02809458","02809446","02785010","02783235","02781247","02769522","02765935","02764566","02762783","02759836","02758740","02757327","02744251","02735595","02680570","02679995","02666638","02637053","02036844","02625026","02567647","02548284","02548098","02548017","02525075","1794655","1776142","1700038","1661674","1657686","1630910","1630798","1618576","1608515","1571998","1543480","1543362","1543879","1527308","757590","741501","741499","719213","685102","679649","679475","678810","679234","676380","676279","667373","660337","627189"],"items":["3.01,5.03,9.01","","","","","","","","","","","","","","","","","","","","","","5,7","","","5,7","","12,7","","","","","12,7","","","","","","","","7,9","","","","","","","","","5,7","","","","","","6,7","","","","","","","5,7","","","","","","","","","","","","","","","","","","5,7","","","","","","","","","","","","","","","","","","","","","",""],"core_type":["8-K","15-12G","4","4","4","4","4","4","SC 13G/A","425","4/A","425","4","4","4","4","4","4","4","425","SC 13D","SC 13D","8-K","8-A12G/A","DEFA14A","8-K","425","8-K","10-Q","4","4","4","8-K","10-Q","4","4","4","4","4","10-Q","8-K","DEF 14A","10-K","SC 13G/A","SC 13G/A","SC 13G/A","S-8","S-8","10-Q","8-K","8-A12G/A","10-Q/A","4","4","4","8-K","4","4","3","4","SC 13G/A","4","8-K","10-Q","SC 13G/A","SC 13G","S-8","10-Q","ARS","DEF 14A","10-K","SC 13G/A","SC 13G/A","SC 13G/A","SC 13G","S-8","10-Q","10-Q","SC 13G/A","4","8-K","8-A12G","10-Q","DEF 14A","10-K","SC 13G","SC 13G","SC 13G","SC 13G","10-Q","SC 13D","5","10-Q","S-8","424B4","S-1MEF","S-1/A","S-1/A","S-1/A","8-A12G","S-1/A","S-1/A","S-1"],"size":[18444,6637,4992,16323,4982,12377,10059,13844,93841,54269,20560,8589,16427,16414,16418,4201,4209,4211,7158,8566,32374,298542,19233,34251,20013,272801,24414,22461,296238,8460,7305,7419,21764,166635,19227,4031,4028,4019,4036,163423,20006,220020,856823,27042,92763,12399,100328,38541,168028,14473,23417,9080,96927,76983,75048,22057,84151,78617,64370,80488,81399,78573,23582,148957,99234,20877,29113,143450,1682,193564,1155374,263783,27507,27623,12199,43981,142332,141511,12175,13971,29131,228904,49782,149613,367739,9698,11257,52304,12518,57163,21290,13846,57575,20759,275665,11630,376508,297496,295602,9271,560424,341459,1224888],"isXBRL":[0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0],"isInlineXBRL":[0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0],"isXBRLNumeric":[null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null],"primaryDocument":["c06444e8vk.htm","c82878e15v12g.htm","xslF345X02/edgar.xml","xslF345X02/edgar.xml","xslF345X02/edgar.xml","xslF345X02/edgar.xml","xslF345X02/edgar.xml","xslF345X02/edgar.xml","a2103013zsc13ga.htm","c82316e425.htm","xslF345X02/bvf-applied_form4amendex.xml","c82032e425.htm","xslF345X02/edgar.xml","xslF345X02/edgar.xml","xslF345X02/edgar.xml","xslF345X02/edgar.xml","xslF345X02/edgar.xml","xslF345X02/edgar.xml","xslF345X02/edgar.xml","a95451e425.txt","a94922sc13d.htm","c81331sc13d.htm","a94826e8vk.htm","a94830a2e8va12gza.htm","a94825defa14a.htm","a94827e8vk.htm","c81238e425.htm","a94190e8vk.htm","a93409e10vq.htm","xslF345X02/edgar.xml","xslF345X02/edgar.xml","xslF345X02/edgar.xml","a92079e8vk.htm","a91282e10vq.htm","xslF345X01/edgar.xml","xslF345X01/edgar.xml","xslF345X01/edgar.xml","xslF345X01/edgar.xml","xslF345X01/edgar.xml","a89791e10vq.htm","a89794e8vk.htm","a89216def14a.htm","a88147ore10vk.htm","a87629sc13gza.htm","a2103013zsc13ga.htm","a2101748zsc13ga.txt","a86759orsv8.htm","a86761orsv8.htm","a85581e10vq.htm","a85577e8vk.htm","a85579a1e8va12gza.htm","a85580a1e10vqza.htm","a2090950z4.htm","a2090783z4.htm","a2090597z4.htm","a84554e8vk.htm","a2089460z4.htm","a2089385z4.htm","a2089040z3.htm","a2088931z4.htm","a2088816zsc13ga.htm","a2088777z4.htm","a84026e8vk.htm","a83441e10vq.htm","a2082537zsc13ga.htm","a2082466zsc13g.htm","a82077orsv8.htm","a81377e10-q.htm","9999999997-02-030473.paper","a79453ddef14a.htm","a79507e10-k.htm","j2858_sc13ga.htm","a79192a2sc13ga.htm","a79197a1sc13ga.htm","doc1.txt","a77350ors-8.htm","a76782e10-q.htm","a74669e10-q.htm","a73522a1sc13ga.txt","srz9056303v1.txt","a72522e8-k.htm","a72518e8-a12g.htm","a71920e10-q.txt","a71601ddef14a.txt","a70303e10-k.txt","a69634sc13g.txt","a69634whsc13g.txt","0001.txt","0001.txt","a66782e10-q.txt","0001.txt","0001.txt","a65469e10-q.txt","s-8.txt","e424b4.txt","s-1mef.txt","s-1a.txt","s-1a.txt","s-1a.txt","e8-a12g.txt","s-1a.txt","s-1a.txt",""],"primaryDocDescription":["CURRENT REPORT","CERT. AND NOTICE OF TERMINATION OF REGISTRATION","PRIMARY DOCUMENT","PRIMARY DOCUMENT","PRIMARY DOCUMENT","PRIMARY DOCUMENT","PRIMARY DOCUMENT","PRIMARY DOCUMENT","","FORM 425","","FILING OF CERTAIN PROSPECTUSES & COMMUNICATIONS","PRIMARY DOCUMENT","PRIMARY DOCUMENT","PRIMARY DOCUMENT","PRIMARY DOCUMENT","PRIMARY DOCUMENT","PRIMARY DOCUMENT","PRIMARY DOCUMENT","FORM 425","SCHEDULE 13D","SCHEDULE 13D","FORM 8-K","POST-EFFECTIVE AM.#2 TO FORM 8-A","SOLICITING MATERIAL UNDER RULE 14A-12","FORM 8-K","FORM 425","FORM 8-K","FORM 10-Q PERIOD ENDED 9-30-03","PRIMARY DOCUMENT","PRIMARY DOCUMENT","PRIMARY DOCUMENT","FORM 8-K","FORM 10-Q PERIOD ENDED 6-30-03","PRIMARY DOCUMENT","PRIMARY DOCUMENT","PRIMARY DOCUMENT","PRIMARY DOCUMENT","PRIMARY DOCUMENT","FORM 10-Q PERIOD ENDED MARCH 31, 2003","FORM 8-K","DEFINITIVE PROXY STATEMENT","FORM 10-K YEAR ENDED 12-31-02","AMENDMENT #3 TO SCHEDULE 13G","SC 13G/A","13G/A","FORM S-8","FORM S-8","FORM 10-Q PERIOD ENDED SEPTEMBER 30, 2002","FORM 8-K","FORM 8-A POST EFFECTIVE AMENDMENT NO.1","FORM 10-Q AMENDMENT NO. 1","FORM 4","FORM 4","FORM4","FORM 8-K","FORM 4","FORM 4","FORM 3","FORM 4","SC 13G/A","FORM 4","FORM 8-K CURRENT REPORT DATED AUGUST 18, 2002","FORM 10-Q PERIOD ENDED JUNE 30, 2002","SC 13G/A","SC 13G","FORM S-8","FORM 10-Q PERIOD ENDED MARCH 31, 2002","AUTO-GENERATED PAPER DOCUMENT","DEFINITIVE PROXY STATEMENT","FORM 10-K YEAR ENDED DECEMBER 31, 2001","SC 13G/A","SCHEDULE 13G/A AMENDMENT #2, WILLIAM D. HUSE","SCHEDULE 13G/A AMENDMENT #1, ALPHA BIOVENTURES","SCHEDULE 13G AMENDMENT","FORM S-8","APPLIED MOLECULAR EVOLUTION, INC.","FORM 10-Q PERIOD ENDED JUNE 30, 2001","AMENDMENT NO.1 TO SCHEDULE 13G","APPLIED MOLECULAR EVOLUTION INC FORM 4","FORM 8-K","FORM 8-A12G","FORM 10-Q PERIOED ENDED MARCH 31, 2000","DEFINITIVE PROXY STATEMENT","FORM 10-K PERIOD ENDED DECEMBER 31, 2000","SCHEDULE 13G","SCHEDULE 13G","FORM SC 13G","SCHEDULE 13G","FORM 10-Q FOR QUARTERLY PERIOD ENDED SEPT.30, 2000","","","FORM 10-Q FOR QUARTER ENDED JUNE 30, 2000","FORM S-8","FORM 424B4","FORM S-1MEF","AMENDMENT NO. 4 TO FORM S-1","AMENDMENT TO FORM S-1","AMENDMENT NO.3 TO FORM S-1","FORM 8-A12G","AMENDMENT #2 TO FORM S-1","FORM S-1 AMENDMENT NO.1","FORM S-1"]},"files":[]}}